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CCL5 Protein (AA 24-91)

CCL5 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE.
产品编号 ABIN7504996
发货至: 中国
  • 抗原 See all CCL5 蛋白
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    蛋白类型
    Recombinant
    产品特性
    AA 24-91
    宿主
    • 17
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    资源
    • 26
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    大肠杆菌(E. Coli)
    序列
    Ser24-Ser91
    产品特性
    A DNA sequence encoding the Human CCL5/RANTES Protein(P13501)(Ser24-Ser91)was expressed with N-SUMO&C-His tag.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CCL5 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
    别名
    CCL5 (CCL5 产品)
    别名
    Rantes Protein, Scya5 Protein, D17S136E Protein, RANTES Protein, SCYA5 Protein, SIS-delta Protein, SISd Protein, TCP228 Protein, eoCP Protein, MuRantes Protein, C-C motif chemokine 5-like Protein, C-C motif chemokine ligand 5 Protein, chemokine (C-C motif) ligand 5 Protein, LOC100230935 Protein, CCL5 Protein, Ccl5 Protein
    背景

    Abbreviation: CCL5,RANTES

    Target Synonym: C-C motif chemokine 5,EoCP,Eosinophil chemotactic cytokine,SIS-delta,Small-inducible cytokine A5,T cell-specific protein P228,TCP228,T-cell-specific protein RANTES,D17S136E,SCYA5

    Background: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. May activate several chemokine receptors including CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils

    分子量

    Calculated MW: 22.3 kDa

    Observed MW: 25 kDa

    UniProt
    P13501
    途径
    Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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