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CD74 Protein (AA 73-296) (His tag)

CD74 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % as determined by reducing SDS-PAGE. Imm
产品编号 ABIN7504958
发货至: 中国
  • 抗原 See all CD74 蛋白
    CD74 (HLA-DR-gamma (CD74))
    蛋白类型
    Recombinant
    产品特性
    AA 73-296
    宿主
    • 11
    • 10
    • 3
    资源
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This CD74 protein is labelled with His tag.
    应用范围
    Immunogen (Imm)
    序列
    Gln73-Met296
    产品特性
    A DNA sequence encoding theHuman CD74 protein (P04233) (73Q-296M) was expressed with a polyhistidine tag at the N-terminus.
    纯度
    > 90 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CD74 蛋白
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    used as Immunogen for (ABIN6999918, ABIN7234286, ABIN7234287 and ABIN7234288)

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from sterile PBS, pH 7.4.
    Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.
    储存条件
    4 °C,-20 °C,-80 °C
    储存方法
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    有效期
    12 months
  • 抗原
    CD74 (HLA-DR-gamma (CD74))
    别名
    CD74 (CD74 产品)
    别名
    DHLAG Protein, HLADG Protein, II Protein, Ia-GAMMA Protein, CLIP Protein, Ii Protein, INVG34 Protein, Iclp-1 Protein, iclp1 Protein, wu:fb11f09 Protein, wu:fb12a01 Protein, wu:fb13d06 Protein, wu:fk94e07 Protein, Iclp-2 Protein, cd74 Protein, iclp2 Protein, zgc:123161 Protein, CD74 molecule Protein, CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) Protein, CD74 molecule, major histocompatibility complex, class II invariant chain a Protein, CD74 molecule, major histocompatibility complex, class II invariant chain b Protein, CD74 Protein, Cd74 Protein, cd74a Protein, cd74b Protein
    背景

    Abbreviation: CD74

    Target Synonym: CD 74,CD74 antigen (invariant polypeptide of major histocompatibility complex,class II antigen-associated),CD74 Molecule,major histocompatibility complex,class II invariant chain,CLIP,DHLAG,Gamma chain of class II antigens,HG2A,HLA class II histocompatibility antigen gamma chain,HLA DR antigens associated invariant chain,HLA DR gamma,HLA-DR antigens-associated invariant chain,HLA-DR-gamma,HLADG,HLADR antigens associated invariant chain,Ia antigen associated invariant chain,Ia antigen-associated invariant chain,Ia associated invariant chain,Ia gamma,Invariant polypeptide of major histocompatibility complex class II antigen associated,la-gamma,Major histocompatibility complex class II invariant chain,MHC HLA DR gamma chain,MHC HLA-DR gamma chain,p33,p35,Protein 41

    Background: Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.

    分子量

    Calculated MW: 26.6 kDa

    Observed MW: 30-33 kDa

    UniProt
    P04233
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Negative Regulation of intrinsic apoptotic Signaling, Cancer Immune Checkpoints
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