PUMA Protein (AA 1-193) (His tag)
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- 抗原 See all PUMA (BBC3) 蛋白
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- 蛋白类型
- Recombinant
- 产品特性
- AA 1-193
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宿主
- 人
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资源
- 大肠杆菌（E. Coli）
- 标记
- This PUMA protein is labelled with His tag.
- 应用范围
- Immunogen (Imm)
- 序列
- Met1-Asn193
- 产品特性
- A DNA sequence encoding the Human PUMA/BBC3 (Q9BXH1-1) (1M-193N) was expressed with a polyhistidine tag at the N-terminus.
- 纯度
- > 90 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product BBC3 蛋白
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BCL2 Binding Component 3 (BBC3) (AA 141-261) protein (His-IF2DI Tag)
BBC3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 90 % by SDS-PAGE gel analyses WB, ELISA
BCL2 Binding Component 3 (BBC3) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
BCL2 Binding Component 3 (BBC3) (AA 76-170) protein (His tag,Strep II tag)BBC3 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant ~95 % WB, ELISA, MS
BCL2 Binding Component 3 (BBC3) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)BBC3 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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used as Immunogen for (ABIN6999884, ABIN7234184, ABIN7234185 and ABIN7234186)
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
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Lyophilized from sterile PBS, pH 7.4., 5 % trehalose, 5 % mannitol, 0.01 % tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization. - 储存条件
- 4 °C,-20 °C,-80 °C
- 储存方法
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- 有效期
- 12 months
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- 抗原
- PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
- 别名
- PUMA (BBC3 产品)
- 别名
- BBC3 Protein, Puma Protein, JFY-1 Protein, JFY1 Protein, PUMA Protein, PUMA/JFY1 Protein, BCL2 binding component 3 Protein, Bcl-2 binding component 3 Protein, BBC3 Protein, Bbc3 Protein, bbc3 Protein
- 背景
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Abbreviation: PUMA,BBC3
Target Synonym: BBC 3,Bbc3,BBC3_HUMAN,BCL 2 binding component 3,Bcl-2-binding component 3,BCL2 binding component 3,JFY 1,JFY-1,JFY1,p53 up regulated modulator of apoptosis,p53 up-regulated modulator of apoptosis,p53 Upregulated Modulator of Apoptosis,PUMA alpha,PUMA/JFY1
Background: Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
- 分子量
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Calculated MW: 20.1 kDa
Observed MW: 20-24 kDa
- UniProt
- Q9BXH1-1
- 途径
- p53 Pathway, Positive Regulation of Endopeptidase Activity
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