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SEZ6 Protein (AA 20-925) (Biotin)

SEZ6 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7504525
发货至: 中国
  • 抗原 See all SEZ6 蛋白
    SEZ6 (Seizure Related 6 Homolog (SEZ6))
    蛋白类型
    Recombinant
    产品特性
    AA 20-925
    宿主
    • 4
    • 1
    • 1
    • 1
    资源
    • 7
    HEK-293 Cells
    标记
    This SEZ6 protein is labelled with Biotin.
    原理
    Biotinylated Human SEZ6 Protein
    序列
    Leu20-His925
    产品特性
    Recombinant Biotinylated Human SEZ6 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus.It contains Leu20-His925.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product SEZ6 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SEZ6 (Seizure Related 6 Homolog (SEZ6))
    别名
    SEZ6 (SEZ6 产品)
    别名
    BSRP-C Protein, D11Bhm177e Protein, mKIAA4158 Protein, sez-6 Protein, seizure related gene 6 Protein, seizure related 6 homolog Protein, Sez6 Protein, SEZ6 Protein
    背景
    Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.
    分子量
    100.7 kDa. Due to glycosylation, the protein migrates to 170-200 kDa based on Tris-Bis PAGE result.
    途径
    Synaptic Membrane
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