SARS-CoV NSP3
宿主: SARS Coronavirus-2 (SARS-CoV-2)
宿主: 大肠杆菌(E. Coli)
Recombinant
> 95 % as determined by Tris-Bis PAGE
限制
仅限研究用
状态
Liquid
缓冲液
Supplied as 0.22 μm filtered solution in 50 mM Tris, 0.1 % Tween, 150 mM NaCl ( pH 9.0).
储存条件
-80 °C
储存方法
Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
有效期
12 months
抗原
SARS-CoV NSP3
(SARS-Coronavirus Nonstructural Protein 3 (SARS-CoV NSP3))
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses.