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ITCH Protein (AA 485-862)

ITCH 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
产品编号 ABIN7504453
发货至: 中国
  • 抗原 See all ITCH 蛋白
    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
    蛋白类型
    Recombinant
    产品特性
    AA 485-862
    宿主
    • 4
    • 2
    • 1
    资源
    • 2
    • 2
    • 1
    大肠杆菌(E. Coli)
    原理
    Human ITCH Protein
    序列
    Arg485-Glu862
    产品特性
    Recombinant Human ITCH Protein is expressed from E.coli without tag.It contains Arg485-Glu862.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product ITCH 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22 μm filtered solution in PBS, 200 mM L-Arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
    别名
    ITCH (ITCH 产品)
    别名
    AIF4 Protein, AIP4 Protein, NAPP1 Protein, dJ468O1.1 Protein, 6720481N21Rik Protein, 8030492O04Rik Protein, A130065M08 Protein, C230047C07Rik Protein, itchy E3 ubiquitin protein ligase Protein, itchy, E3 ubiquitin protein ligase Protein, ITCH Protein, Itch Protein
    背景
    Itch or itchy E3 is a member of the homologous to E6-associated protein C-terminus (HECT)-type family of E3 ligases, with the protein-interacting WW-domains for the recruitment of substrate and the HECT domain for the transfer of ubiquitin to the substrate, and its deletion results in an itchy phenotype with constant skin scratching and multi-organ inflammation.
    分子量
    44.98 kDa same as Tris-Bis PAGE result.
    NCBI登录号
    NP_113671
    途径
    Activation of Innate immune Response, CXCR4-mediated Signaling Events
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