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FLT3 Protein (AA 27-541) (Biotin)

FLT3 宿主: 人 宿主: CHO Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7504335
发货至: 中国
  • 抗原 See all FLT3 蛋白
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    蛋白类型
    Recombinant
    产品特性
    AA 27-541
    宿主
    • 15
    • 6
    • 1
    资源
    • 14
    • 4
    • 2
    • 1
    • 1
    CHO Cells
    标记
    This FLT3 protein is labelled with Biotin.
    原理
    Biotinylated Human FLT3/Flk-2 Protein
    序列
    Asn27-Asn541
    产品特性
    Recombinant Biotinylated Human FLT3/Flk-2 Protein is expressed from CHO with His tag and Avi tag at the C-Terminus.It contains Asn27-Asn541.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product FLT3 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))
    别名
    FLT3 (FLT3 产品)
    别名
    FLT3 Protein, B230315G04 Protein, CD135 Protein, Flk-2 Protein, Flk2 Protein, Flt-3 Protein, Ly72 Protein, wmfl Protein, FLK-2 Protein, FLK2 Protein, STK1 Protein, fms related tyrosine kinase 3 Protein, FMS-like tyrosine kinase 3 Protein, fms-related tyrosine kinase 3 Protein, FLT3 Protein, Flt3 Protein
    背景
    The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.
    分子量
    61.20 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
    途径
    RTK signaling
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