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Claudin 4 Protein-VLP (CLDN4) (AA 1-209)

CLDN4 宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC
产品编号 ABIN7504302
发货至: 中国
  • 抗原 See all Claudin 4 (CLDN4) 蛋白
    Claudin 4 (CLDN4)
    蛋白类型
    VLP
    产品特性
    AA 1-209
    宿主
    • 9
    • 2
    • 1
    资源
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    原理
    Human Claudin 4 Protein-VLP
    序列
    Met1-Val209
    产品特性
    Recombinant Human Claudin 4 Protein-VLP is expressed from HEK293.It contains Met1-Val209.
    纯度
    > 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product CLDN4 蛋白
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
    储存条件
    -80 °C
    储存方法
    Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Claudin 4 (CLDN4)
    别名
    Claudin 4 (CLDN4 产品)
    别名
    CPE-R Protein, CPER Protein, CPETR Protein, CPETR1 Protein, WBSCR8 Protein, hCPE-R Protein, Cep-r Protein, Cpetr Protein, Cpetr1 Protein, CLDN4 Protein, cper Protein, cpe-r Protein, cpetr Protein, cpetr1 Protein, hcpe-r Protein, wbscr8 Protein, claudin 4 Protein, claudin 4 L homeolog Protein, CLDN4 Protein, Cldn4 Protein, cldn4 Protein, cldn4.L Protein
    背景
    Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.
    分子量
    23.31 kDa.
    UniProt
    O14493
    途径
    Hepatitis C
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