Supplied as 0.22 μm filtered solution in PBS ( pH 7.4).
储存条件
-80 °C
储存方法
Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
有效期
12 months
抗原
SLC3A2
(Solute Carrier Family 3 (Activators of Dibasic and Neutral Amino Acid Transport), Member 2 (SLC3A2))
4F2 Protein, 4F2HC Protein, 4T2HC Protein, CD98 Protein, CD98HC Protein, MDU1 Protein, NACAE Protein, Mdu1 Protein, MGC53951 Protein, slc3a2 Protein, MGC53965 Protein, SLC3A2 Protein, AI314110 Protein, Cd98 Protein, Ly-10 Protein, Ly-m10 Protein, Ly10 Protein, Mgp-2hc Protein, fc65h12 Protein, wu:fc65h12 Protein, id:ibd1327 Protein, sb:cb519 Protein, wu:fe14a07 Protein, wu:fq18d12 Protein, zgc:55813 Protein, solute carrier family 3 member 2 Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2 L homeolog Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2 S homeolog Protein, solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2a Protein, solute carrier family 3 (amino acid transporter heavy chain), member 2b Protein, SLC3A2 Protein, Slc3a2 Protein, slc3a2.L Protein, slc3a2.S Protein, slc3a2a Protein, slc3a2b Protein
背景
The type II transmembrane protein CD98, best known as the heavy chain of the heterodimeric amino acid transporters (HAT), is required for the surface expression and basolateral localization of this transporter complex in polarized epithelial cells. CD98 also interacts with beta1 integrins resulting in an increase in their affinity for ligand. In this study we explored the role of the transmembrane and cytoplasmic domains of CD98 on integrin-dependent cell adhesion and migration in polarized renal epithelial cells.
分子量
72.38 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Tris-Bis PAGE result.