Klotho beta Protein (KLB) (His tag)
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- 抗原 See all Klotho beta (KLB) 蛋白
- Klotho beta (KLB)
- 蛋白类型
- Recombinant
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宿主
- 大鼠
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资源
- HEK-293 Cells
- 标记
- This Klotho beta protein is labelled with His tag.
- 原理
- Rat Klotho beta / KLB Protein, His Tag
- 序列
- Phe 53 - Pro 994
- 产品特性
- Rat Klotho beta, His Tag is expressed from human 293 cells (HEK293). It contains AA Phe 53 - Pro 994 (Accession # D3Z8T6-1).
- 纯度
- 90 %
- 内毒素水平
- 1.0 EU per μg
- Top Product
- Discover our top product KLB 蛋白
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Klotho beta (KLB) protein (His tag)
KLB 宿主: 人 宿主: HEK-293 Cells Recombinant > 95% as determined by Tris-Bis PAGE,> 95% as determined by HPLC
Klotho beta (KLB) (AA 53-994) protein (His tag)KLB 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
Klotho beta (KLB) proteinKLB 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 95 % SDS, WB, ELISA, IP
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- 说明
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This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 110.5 kDa. The protein migrates as 130-145 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- Klotho beta (KLB)
- 别名
- Klotho beta (KLB 产品)
- 别名
- KLB Protein, BKL Protein, AV071179 Protein, betaKlotho Protein, Klb-ps1 Protein, RGD1308227 Protein, klotho beta Protein, KLB Protein, Klb Protein
- 背景
- KLB (Klotho Beta) is a Protein Coding gene. Among its related pathways are RET signaling and HIV Life Cycle. GO annotations related to this gene include hydrolase activity, hydrolyzing O-glycosyl compounds and fibroblast growth factor binding. An important paralog of this gene is KL. Klotho Beta is a regulator in multiple metabolic processes, while its role in cancer remains unclear. We found the expression of βKlotho was down-regulated in human hepatocellular carcinoma tissues compared with that in paired adjacent non-tumourous liver tissues. Hepatoma cells also showed decreased expression of βKlotho compared with normal hepatocyte cells. Reintroduction of βKlotho into hepatoma cells inhibited their proliferation.
- 分子量
- 110.5 kDa
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Growth Factor Binding
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