CXCR3 Protein-VLP
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- 抗原 See all CXCR3 蛋白
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
- 蛋白类型
- VLP
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CXCR3 Full Length Protein (VLP)
- 序列
- Val 2 - Leu 368
- 产品特性
- Human CXCR3 Full Length Protein-VLP is expressed from human 293 cells (HEK293). It contains AA Val 2 - Leu 368 (Accession # P49682-1).
- 内毒素水平
- 1.0 EU per μg
- Top Product
- Discover our top product CXCR3 蛋白
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Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-53) protein (mFc Tag)
CXCR3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-53) protein (Fc Tag)CXCR3 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) proteinCXCR3 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-368) protein (GST tag)CXCR3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 1-53) protein (GST tag)CXCR3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 3 (CXCR3) (AA 121-220) protein (GST tag)CXCR3 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, Arginine, pH 7.4
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))
- 别名
- CXCR3 (CXCR3 产品)
- 背景
- Chemokines are proteins which induce chemotaxis, promote differentiation of immune cells, and cause tissue extravasation. Given these properties, their role in anti-tumor immune response in the cancer environment is of great interest. Although immunotherapy has shown clinical benefit for some cancer patients, other patients do not respond. One of the mechanisms of resistance to checkpoint inhibitors may be chemokine signaling. The CXCL9, -10, -11/CXCR3 axis regulates immune cell migration, differentiation, and activation, leading to tumor suppression (paracrine axis). However, there are some reports that show involvements of this axis in tumor growth and metastasis (autocrine axis). Thus, a better understanding of CXCL9, -10, -11/CXCR3 axis is necessary to develop effective cancer control.
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