Claudin 9 Protein-VLP (CLDN9)
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- 抗原 See all Claudin 9 (CLDN9) 蛋白
- Claudin 9 (CLDN9)
- 蛋白类型
- VLP
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human Claudin-9 / CLDN9 Full Length Protein (VLP)
- 序列
- Met 1 -Val 217
- 产品特性
- Human Claudin-9 Full Length Protein-VLP is expressed from human 293 cells (HEK293). It contains AA Met 1 -Val 217 (Accession # O95484-1).
- 内毒素水平
- 1.0 EU per μg
- Top Product
- Discover our top product CLDN9 蛋白
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, Arginine, pH 7.4
- 储存条件
- -80 °C
- 储存方法
- -70°C
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- 抗原
- Claudin 9 (CLDN9)
- 别名
- Claudin-9 (CLDN9 产品)
- 别名
- CLDN9 Protein, nmf329 Protein, claudin 9 Protein, CLDN9 Protein, Cldn9 Protein
- 背景
- Claudin-9 belongs to the claudin family. Claudins constitute integral membrane proteins responsible for solute and electrolyte permeability of the tight junction that serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Tight junctions also play a critical role in maintaining cell polarity and signal transductions. Claudin-9 creates charge specific channels in the paracellular space, plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity, is required to preserve sensory cells in the hearing organ because claudin-9-defective tight junctions fail to shield the basolateral side of hair cells from the K+-rich endolymph. Its ion barrier function is essential in the cochlea, but appears to be dispensable in other organs. Is one of the entry cofactors for hepatitis C virus, it enables HCV entry into target cells just as efficiently as CLDN1.
- 途径
- Cell-Cell Junction Organization, Hepatitis C
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