HHLA2 Protein (Biotin,His-Avi Tag)
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- 抗原 See all HHLA2 蛋白
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- 蛋白类型
- Recombinant
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This HHLA2 protein is labelled with Biotin,His-Avi Tag.
- 原理
- Biotinylated Cynomolgus B7-H7 / HHLA2 Protein, His,Avitag™
- 序列
- Ile 21 - Asn 345
- 产品特性
- Biotinylated Cynomolgus B7-H7, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Asn 345 (Accession # XP_005548285.1).
- 纯度
- 90 %
- 内毒素水平
- 1.0 EU per μg
- Top Product
- Discover our top product HHLA2 蛋白
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- 说明
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This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,10xHis , Avi) The protein has a calculated MW of 39.1 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
- 别名
- B7-H7 (HHLA2 产品)
- 别名
- B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
- 背景
- B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
- 分子量
- 39.1 kDa
- NCBI登录号
- XP_005548285
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