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HRH3 蛋白

HRH3 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491683
发货至: 中国
  • 抗原 See all HRH3 蛋白
    HRH3 (Histamine Receptor H3 (HRH3))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 2
    • 2
    • 1
    资源
    • 2
    • 2
    • 1
    HEK-293 Cells
    原理
    Human HRH3 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product HRH3 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    HRH3 (Histamine Receptor H3 (HRH3))
    别名
    HRH3 (HRH3 产品)
    别名
    GPCR97 Protein, HH3R Protein, AW049250 Protein, H3R Protein, histamine receptor H3 Protein, HRH3 Protein, Hrh3 Protein
    背景
    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
    分子量
    The human full length HRH3 protein has a MW of 48.7 kDa
    UniProt
    Q9Y5N1
    途径
    cAMP Metabolic Process, Feeding Behaviour
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