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G Protein-Coupled Receptor 133 Protein (GPR133)

GPR133 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491529
发货至: 中国
  • 抗原 See all G Protein-Coupled Receptor 133 (GPR133) 蛋白
    G Protein-Coupled Receptor 133 (GPR133)
    蛋白类型
    Synthetic Nanodisc
    宿主
    资源
    • 1
    HEK-293 Cells
    原理
    Human ADGRD1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    G Protein-Coupled Receptor 133 (GPR133)
    别名
    ADGRD1 (GPR133 产品)
    别名
    GPR133 Protein, zgc:103546 Protein, PGR25 Protein, E230012M21Rik Protein, adhesion G protein-coupled receptor D1 Protein, ADGRD1 Protein, adgrd1 Protein, Adgrd1 Protein
    背景
    The adhesion G-protein-coupled receptors (GPCRs), including GPR133, are membrane-bound proteins with long N termini containing multiple domains. GPCRs, or GPRs, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.
    分子量
    The human full length ADGRD1 protein has a MW of 96.5 kDa
    UniProt
    Q6QNK2
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