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BDKRB2 蛋白

BDKRB2 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491547
发货至: 中国
  • 抗原 See all BDKRB2 蛋白
    BDKRB2 (Bradykinin Receptor B2 (BDKRB2))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 4
    • 2
    • 1
    • 1
    资源
    • 3
    • 2
    • 2
    • 1
    HEK-293 Cells
    原理
    Human BDKRB2 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product BDKRB2 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    BDKRB2 (Bradykinin Receptor B2 (BDKRB2))
    别名
    BDKRB2 (BDKRB2 产品)
    别名
    BDKRB2 Protein, b2r Protein, bk2 Protein, bk-2 Protein, bkr2 Protein, brb2 Protein, kinrec Protein, B2R Protein, BK-2 Protein, BK2 Protein, BKR2 Protein, BRB2 Protein, B2BKR Protein, B2BRA Protein, B(2) Protein, B2 Protein, BK2R Protein, Bdkrb2 Protein, bradykinin receptor B2 Protein, bradykinin receptor, beta 2 Protein, bradykinin type 2 receptor Protein, Bdkrb2 Protein, BDKRB2 Protein, bdkrb2 Protein, kinrec Protein, B2R Protein
    背景
    This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. Bradykinin is released upon activation by pathophysiologic conditions such as trauma and inflammation, and binds to its kinin receptors, B1 and B2. The B2 receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. [provided by RefSeq, Apr 2020]
    分子量
    The human full length BDKRB2 protein has a MW of 44.5 kDa
    UniProt
    P30411
    途径
    ACE Inhibitor Pathway, Negative Regulation of intrinsic apoptotic Signaling
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