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MC4R 蛋白

MC4R 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491693
发货至: 中国
  • 抗原 See all MC4R 蛋白
    MC4R (Melanocortin 4 Receptor (MC4R))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 6
    • 2
    • 1
    资源
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    原理
    Human MC4R full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
    Top Product
    Discover our top product MC4R 蛋白
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    MC4R (Melanocortin 4 Receptor (MC4R))
    别名
    MC4R (MC4R 产品)
    别名
    zMC4 Protein, si:dkey-151m6.62 Protein, mc4r Protein, MC4R Protein, LOC100218148 Protein, Mc4-r Protein, melanocortin 4 receptor Protein, mc4r Protein, MC4R Protein, Mc4r Protein
    背景
    The protein is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity.
    分子量
    The human full length MC4R protein has a MW of 36.9 kDa
    UniProt
    P32245
    途径
    Hormone Transport, cAMP Metabolic Process, Feeding Behaviour
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