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- 抗原 See all XCR1 蛋白
- XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human XCR1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Chemokine (C Motif) Receptor 1 (XCR1) (AA 1-31) protein (Fc Tag)
XCR1 宿主: 人 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- XCR1 (Chemokine (C Motif) Receptor 1 (XCR1))
- 别名
- XCR1 (XCR1 产品)
- 别名
- CCXCR1-L Protein, XCR1 Protein, CCXCR1 Protein, GPR5 Protein, Ccxcr1 Protein, Gpr5 Protein, mXcr1 Protein, X-C motif chemokine receptor 1 Protein, chemokine (C motif) receptor 1a, duplicate 1 Protein, chemokine (C motif) receptor 1 Protein, XCR1 Protein, xcr1a.1 Protein, Xcr1 Protein
- 背景
- The protein is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Several alternatively spliced transcript variants encoding the same protein have been found for this gene.
- 分子量
- The human full length XCR1 protein has a MW of 38.5 kDa
- UniProt
- P46094
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