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CX3CR1 蛋白

CX3CR1 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491617
发货至: 中国
  • 抗原 See all CX3CR1 蛋白
    CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 6
    • 3
    资源
    • 3
    • 3
    • 2
    • 1
    HEK-293 Cells
    原理
    Human CX3CR1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
    别名
    CX3CR1 (CX3CR1 产品)
    别名
    CCRL1 Protein, CMKBRL1 Protein, CMKDR1 Protein, GPR13 Protein, GPRV28 Protein, V28 Protein, Rbs11 Protein, C-X3-C motif chemokine receptor 1 Protein, chemokine (C-X3-C motif) receptor 1 Protein, CX3C chemokine receptor 1 Protein, CX3CR1 Protein, Cx3cr1 Protein, LOC100559882 Protein
    背景
    Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS.
    分子量
    The human full length CX3CR1 protein has a MW of 40.4 kDa
    UniProt
    P49238
    途径
    Cellular Response to Molecule of Bacterial Origin
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