CX3CR1 蛋白
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- 抗原 See all CX3CR1 蛋白
- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CX3CR1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))
- 别名
- CX3CR1 (CX3CR1 产品)
- 别名
- CCRL1 Protein, CMKBRL1 Protein, CMKDR1 Protein, GPR13 Protein, GPRV28 Protein, V28 Protein, Rbs11 Protein, C-X3-C motif chemokine receptor 1 Protein, chemokine (C-X3-C motif) receptor 1 Protein, CX3C chemokine receptor 1 Protein, CX3CR1 Protein, Cx3cr1 Protein, LOC100559882 Protein
- 背景
- Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS.
- 分子量
- The human full length CX3CR1 protein has a MW of 40.4 kDa
- UniProt
- P49238
- 途径
- Cellular Response to Molecule of Bacterial Origin
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