F2RL3 蛋白
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- 抗原 See all F2RL3 蛋白
- F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human F2RL3 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- F2RL3 (Coagulation Factor II (Thrombin) Receptor-Like 3 (F2RL3))
- 别名
- F2RL3 (F2RL3 产品)
- 别名
- F2RL3 Protein, PAR4 Protein, F2R like thrombin or trypsin receptor 3 Protein, F2R like thrombin/trypsin receptor 3 Protein, coagulation factor II (thrombin) receptor-like 3 Protein, F2RL3 Protein, F2rl3 Protein
- 背景
- A member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients.
- 分子量
- The human full length F2RL3 protein has a MW of 41.1 kDa
- UniProt
- Q96RI0
- 途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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