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GLP2R 蛋白

GLP2R 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491655
发货至: 中国
  • 抗原 See all GLP2R 蛋白
    GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 6
    • 2
    • 1
    资源
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    原理
    Human GLP2R full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))
    别名
    GLP2R (GLP2R 产品)
    别名
    9530092J08Rik Protein, GLP-2 Protein, glucagon like peptide 2 receptor Protein, glucagon-like peptide 2 receptor Protein, GLP2R Protein, Glp2r Protein
    背景
    A G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis.
    分子量
    The human full length GLP2R protein has a MW of 63.0 kDa
    UniProt
    O95838
    途径
    Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour
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