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SCARB1 蛋白

SCARB1 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491725
发货至: 中国
  • 抗原 See all SCARB1 蛋白
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 9
    • 2
    • 1
    资源
    • 8
    • 2
    • 1
    • 1
    HEK-293 Cells
    原理
    Human SCARB1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))
    别名
    SCARB1 (SCARB1 产品)
    别名
    cb1015 Protein, SCARB1 Protein, Scarb1 Protein, CD36L1 Protein, CLA-1 Protein, CLA1 Protein, HDLQTL6 Protein, SR-BI Protein, SRB1 Protein, AI120173 Protein, CD36 Protein, Cd36l1 Protein, Cla-1 Protein, Cla1 Protein, D5Ertd460e Protein, Hdlq1 Protein, Hlb398 Protein, SR-B1 Protein, SRBI Protein, Srb1 Protein, mSR-BI Protein, scavenger receptor class B, member 1 Protein, scavenger receptor class B member 1 Protein, scarb1 Protein, SCARB1 Protein, Scarb1 Protein, CpipJ_CPIJ014332 Protein, CpipJ_CPIJ019101 Protein
    背景
    The protein is a plasma membrane receptor for high density lipoprotein cholesterol (HDL). The encoded protein mediates cholesterol transfer to and from HDL. In addition, this protein is a receptor for hepatitis C virus glycoprotein E2. Several transcript variants encoding different isoforms have been found for this gene.
    分子量
    The human full length SCARB1 protein has a MW of 60.9 kDa
    UniProt
    Q8WTV0
    途径
    Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome
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