电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CLPTM1 蛋白

CLPTM1 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491611
发货至: 中国
  • 抗原 See all CLPTM1 蛋白
    CLPTM1 (Cleft Lip and Palate Associated Transmembrane Protein 1 (CLPTM1))
    蛋白类型
    Synthetic Nanodisc
    宿主
    资源
    • 1
    HEK-293 Cells
    原理
    Human CLPTM1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CLPTM1 (Cleft Lip and Palate Associated Transmembrane Protein 1 (CLPTM1))
    别名
    CLPTM1 (CLPTM1 产品)
    别名
    CLPTM1 Protein, cb102 Protein, sb:cb102 Protein, zgc:100803 Protein, HS9 Protein, N14 Protein, CLPTM1, transmembrane protein Protein, cleft lip and palate associated transmembrane protein 1 Protein, CLPTM1 Protein, clptm1 Protein, Bm1_06285 Protein, PTRG_03625 Protein, Clptm1 Protein
    背景
    Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate. Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one.
    分子量
    The human full length CLPTM1 protein has a MW of 76.1 kDa
    UniProt
    O96005
You are here:
客服