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- 抗原 See all CXCR7 蛋白
- CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CXCR7 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 1-362) protein (GST tag)
CXCR7 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 7 (CXCR7) (AA 1-40) protein (Fc Tag)CXCR7 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))
- 别名
- ACKR3 (CXCR7 产品)
- 别名
- CMKOR1 Protein, CXC-R7 Protein, CXCR-7 Protein, CXCR7 Protein, GPR159 Protein, RDC-1 Protein, RDC1 Protein, AW541270 Protein, Cmkor1 Protein, Cxcr7 Protein, Rdc1 Protein, ackr3 Protein, cxcr7 Protein, rdc1 Protein, xcxcr7 Protein, atypical chemokine receptor 3 Protein, ORF 74; similar to Kaposi's sarcoma-associated herpesvirus ORF 74 Protein, atypical chemokine receptor 3 L homeolog Protein, ACKR3 Protein, MmrVgp88 Protein, Ackr3 Protein, ackr3.L Protein
- 背景
- A member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
- 分子量
- The human full length CXCR7 protein has a MW of 41.5 kDa
- UniProt
- P25106
- 途径
- Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling
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