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- 抗原 See all CXCR1 蛋白
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CXCR1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product CXCR1 蛋白
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Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 1-350) protein (GST tag)
CXCR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 1 (CXCR1) (AA 1-39) protein (Fc Tag)CXCR1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- 别名
- CXCR1 (CXCR1 产品)
- 别名
- C-C Protein, C-C-CKR-1 Protein, CD128 Protein, CD181 Protein, CDw128a Protein, CKR-1 Protein, CMKAR1 Protein, IL8R1 Protein, IL8RA Protein, IL8RBA Protein, Il8ra Protein, CXCR-1 Protein, IL-8RA Protein, CXCR2 Protein, IL8RB Protein, cxcr1 Protein, cxcr2 Protein, C-X-C motif chemokine receptor 1 Protein, chemokine (C-X-C motif) receptor 1 Protein, C-X-C chemokine receptor type 1 Protein, C-X-C motif chemokine receptor 1 S homeolog Protein, CXCR1 Protein, Cxcr1 Protein, LOC100461947 Protein, cxcr1.S Protein
- 背景
- The protein is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
- 分子量
- The human full length CXCR1 protein has a MW of 39.8 kDa
- UniProt
- P25024
- 途径
- cAMP Metabolic Process
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