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- 抗原 See all C5AR1 蛋白
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human C5AR1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Complement Component 5a Receptor 1 (C5AR1) (AA 1-350) protein (GST tag)
C5AR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Complement Component 5a Receptor 1 (C5AR1) (AA 241-350) protein (GST tag)C5AR1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Complement Component 5a Receptor 1 (C5AR1) (AA 1-37) protein (Fc Tag)C5AR1 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Complement Component 5a Receptor 1 (C5AR1) protein (Myc-DYKDDDDK Tag)C5AR1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
- 别名
- C5AR1 (C5AR1 产品)
- 别名
- C5A Protein, C5AR Protein, C5R1 Protein, CD88 Protein, C5aR Protein, C5r1 Protein, Cd88 Protein, D7Msu1 Protein, GPR77 Protein, complement C5a receptor 1 Protein, complement component 5a receptor 1 Protein, C5AR1 Protein, C5ar1 Protein, c5ar1 Protein
- 背景
- Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production
- 分子量
- The human full length C5AR1 protein has a MW of 39.3 kDa
- UniProt
- P21730
- 途径
- Complement System
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