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- 抗原 See all CXCR4 蛋白
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CXCR4 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-80) protein (His-IF2DI Tag)
CXCR4 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-352) protein (GST tag)CXCR4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) protein (GST tag)CXCR4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-38) protein (Fc Tag)CXCR4 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- 别名
- CXCR4 (CXCR4 产品)
- 别名
- CD184 Protein, D2S201E Protein, FB22 Protein, HM89 Protein, HSY3RR Protein, LAP3 Protein, LCR1 Protein, LESTR Protein, NPY3R Protein, NPYR Protein, NPYRL Protein, NPYY3R Protein, WHIM Protein, Cmkar4 Protein, PB-CKR Protein, PBSF/SDF-1 Protein, Sdf1r Protein, CXC-R4-B Protein, CXCR-4-B Protein, cd184 Protein, cxcr4 Protein, fb22 Protein, hm89 Protein, hsy3rr Protein, lap3 Protein, lcr1 Protein, lestr Protein, npy3r Protein, npyr Protein, npyrl Protein, npyy3r Protein, xcxcr4 Protein, CXC-R4 Protein, CXCR-4 Protein, d2s201e Protein, whim Protein, CXC-R4-A Protein, CXCR-4-A Protein, xCXCR4 Protein, CXCR4 Protein, cb403 Protein, zgc:109863 Protein, cb824 Protein, C-X-C motif chemokine receptor 4 Protein, chemokine (C-X-C motif) receptor 4 Protein, C-X-C motif chemokine receptor 4 S homeolog Protein, C-X-C chemokine receptor type 4 Protein, C-X-C motif chemokine receptor 4 L homeolog Protein, chemokine (C-X-C motif), receptor 4b Protein, chemokine (C-X-C motif) receptor 4a Protein, CXCR4 Protein, Cxcr4 Protein, cxcr4.S Protein, cxcr4 Protein, LOC100049444 Protein, cxcr4.L Protein, cxcr4b Protein, cxcr4a Protein
- 背景
- A CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome.
- 分子量
- The human full length CXCR4 protein has a MW of 39.7 kDa
- UniProt
- P61073
- 途径
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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