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CD151 Protein (CD151)

CD151 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491574
发货至: 中国
  • 抗原 See all CD151 蛋白
    CD151
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 3
    • 1
    资源
    • 2
    • 2
    HEK-293 Cells
    原理
    Human CD151 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CD151
    别名
    CD151 (CD151 产品)
    别名
    CD151 Protein, MGC83668 Protein, gp27 Protein, mer2 Protein, raph Protein, sfa1 Protein, peta-3 Protein, tspan24 Protein, PETA-3 Protein, SFA-1 Protein, Tspan24 Protein, GP27 Protein, MER2 Protein, RAPH Protein, SFA1 Protein, TSPAN24 Protein, CD151 molecule Protein, CD151 molecule (Raph blood group) L homeolog Protein, CD151 molecule (Raph blood group) Protein, CD151 antigen Protein, CD151 Protein, cd151.L Protein, cd151 Protein, Cd151 Protein
    背景
    The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
    分子量
    The human full length CD151 protein has a MW of 28.3 kDa
    UniProt
    P48509
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