CD151 Protein (CD151)
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- 抗原 See all CD151 蛋白
- CD151
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CD151 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CD151
- 别名
- CD151 (CD151 产品)
- 别名
- CD151 Protein, MGC83668 Protein, gp27 Protein, mer2 Protein, raph Protein, sfa1 Protein, peta-3 Protein, tspan24 Protein, PETA-3 Protein, SFA-1 Protein, Tspan24 Protein, GP27 Protein, MER2 Protein, RAPH Protein, SFA1 Protein, TSPAN24 Protein, CD151 molecule Protein, CD151 molecule (Raph blood group) L homeolog Protein, CD151 molecule (Raph blood group) Protein, CD151 antigen Protein, CD151 Protein, cd151.L Protein, cd151 Protein, Cd151 Protein
- 背景
- The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
- 分子量
- The human full length CD151 protein has a MW of 28.3 kDa
- UniProt
- P48509
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