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- 抗原 See all STEAP1 蛋白
- STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human STEAP1 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 1-339) protein (GST tag)
STEAP1 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) (AA 3-69), (partial) protein (GST tag)STEAP1 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1) protein (Myc-DYKDDDDK Tag)STEAP1 宿主: 人 宿主: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
- 别名
- STEAP1 (STEAP1 产品)
- 别名
- PRSS24 Protein, STEAP Protein, STEAP1 Protein, 2410007B19Rik Protein, Prss24 Protein, Steap Protein, STEAP family member 1 Protein, six transmembrane epithelial antigen of the prostate 1 Protein, STEAP1 Protein, Steap1 Protein
- 背景
- STEAP1 is a cell-surface biomolecule composed by sixtransmembrane domains connected by intra- and extracellular loops. It is commonly found overexpressed in several types of cancers, namely in PCa, and is preferentially located at the tight or gap junctions. However, in nontumoural tissues and vital organs, STEAP1 protein presents low or absent expression, unveiling considerable specificity for cancer environment. Taking into account STEAP1 predicted transmembrane topology and cellular localization, it has been hypothesized that STEAP1 may play an important role as a transporter protein and can be involved in intercellular communication.
- 分子量
- The human full length STEAP1 protein has a MW of 39.9 kDa
- UniProt
- Q9UHE8
- 途径
- Transition Metal Ion Homeostasis
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