电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

STEAP1 蛋白

STEAP1 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491743
发货至: 中国
  • 抗原 See all STEAP1 蛋白
    STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 4
    • 1
    资源
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    原理
    Human STEAP1 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    STEAP1 (Six Transmembrane Epithelial Antigen of The Prostate 1 (STEAP1))
    别名
    STEAP1 (STEAP1 产品)
    别名
    PRSS24 Protein, STEAP Protein, STEAP1 Protein, 2410007B19Rik Protein, Prss24 Protein, Steap Protein, STEAP family member 1 Protein, six transmembrane epithelial antigen of the prostate 1 Protein, STEAP1 Protein, Steap1 Protein
    背景
    STEAP1 is a cell-surface biomolecule composed by sixtransmembrane domains connected by intra- and extracellular loops. It is commonly found overexpressed in several types of cancers, namely in PCa, and is preferentially located at the tight or gap junctions. However, in nontumoural tissues and vital organs, STEAP1 protein presents low or absent expression, unveiling considerable specificity for cancer environment. Taking into account STEAP1 predicted transmembrane topology and cellular localization, it has been hypothesized that STEAP1 may play an important role as a transporter protein and can be involved in intercellular communication.
    分子量
    The human full length STEAP1 protein has a MW of 39.9 kDa
    UniProt
    Q9UHE8
    途径
    Transition Metal Ion Homeostasis
You are here:
Blank Blank Blank Blank
Blank Blank Blank Blank
客服
Close menu