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- 抗原 See all GLUT4 (SLC2A4) 蛋白
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human SLC2A4 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (AA 467-509) protein (GST tag)
SLC2A4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (AA 1-509) protein (GST tag)SLC2A4 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4) (AA 46-78) protein (Fc Tag)SLC2A4 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
- 别名
- SLC2A4 (SLC2A4 产品)
- 别名
- GLUT4 Protein, Glut-4 Protein, Glut4 Protein, glut4 Protein, slc2a4 Protein, SLC2A4 Protein, solute carrier family 2 member 4 Protein, solute carrier family 2 (facilitated glucose transporter), member 4 Protein, solute carrier family 2 (facilitated glucose transporter), member 4 L homeolog Protein, SLC2A4 Protein, Slc2a4 Protein, GLUT4 Protein, slc2a4.L Protein
- 背景
- This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]
- 分子量
- The human full length SLC2A4 protein has a MW of 54.6 kDa
- UniProt
- P14672
- 途径
- AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effect
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