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- 抗原 See all CCR6 蛋白
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CCR6 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 1-39) protein (Fc Tag)
CCR6 宿主: 小鼠 宿主: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 1-47) protein (Fc Tag)CCR6 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Chemokine (C-C Motif) Receptor 6 (CCR6) (AA 1-47) protein (mFc Tag)CCR6 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
- 别名
- CCR6 (CCR6 产品)
- 别名
- BN-1 Protein, C-C CKR-6 Protein, CC-CKR-6 Protein, CCR-6 Protein, CD196 Protein, CKR-L3 Protein, CKRL3 Protein, CMKBR6 Protein, DCR2 Protein, DRY6 Protein, GPR29 Protein, GPRCY4 Protein, STRL22 Protein, Cmkbr6 Protein, KY411 Protein, C-C motif chemokine receptor 6 Protein, chemokine (C-C motif) receptor 6 Protein, CCR6 Protein, Ccr6 Protein
- 背景
- The protein is a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
- 分子量
- The human full length CCR6 protein has a MW of 42.5 kDa
- UniProt
- P51684
- 途径
- cAMP Metabolic Process
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