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- 抗原 See all FSHR 蛋白
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
- 蛋白类型
- Synthetic Nanodisc
- 宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human FSHR full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
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Follicle Stimulating Hormone Receptor (FSHR) (AA 35-240) protein (His-IF2DI Tag)
FSHR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Follicle Stimulating Hormone Receptor (FSHR) (AA 18-120) protein (GST tag)FSHR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP
Follicle Stimulating Hormone Receptor (FSHR) (AA 18-366), (Extracellular) protein (His tag)FSHR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant > 90 % SDS
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
- 别名
- FSHR (FSHR 产品)
- 别名
- FSHRO Protein, LGR1 Protein, ODG1 Protein, FSH-R Protein, eFSHR Protein, FSHRE Protein, fshr Protein, FSHR Protein, fshr-A Protein, GTHR-I Protein, zfGTHR-I Protein, LOC100304505 Protein, follicle stimulating hormone receptor Protein, follicle stimulating hormone receptor L homeolog Protein, follicle-stimulating hormone receptor Protein, FSHR Protein, fshr Protein, Fshr Protein, fshr.L Protein, Bm1_17785 Protein, LOC100304505 Protein
- 背景
- The protein belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.
- 分子量
- The human full length FSHR protein has a MW of 78.3 kDa
- UniProt
- P23945
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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