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CD37 蛋白

TSPAN26 宿主: 人 宿主: HEK-293 Cells Synthetic Nanodisc
产品编号 ABIN7491580
发货至: 中国
  • 抗原 See all CD37 (TSPAN26) 蛋白
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    蛋白类型
    Synthetic Nanodisc
    宿主
    • 8
    • 1
    资源
    • 4
    • 2
    • 2
    • 1
    HEK-293 Cells
    原理
    Human CD37 full length protein-synthetic nanodisc
    产品特性
    Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
  • 说明

    Advantages of Synthetic Nanodiscs:

    • Highly purified membrane proteins
    • High solubility in aqueous solutions
    • High stability
    • Proteins are in a native membrane environment and remain biologically active
    • No detergent and can be used for cell-based assays
    • No MSP backbone proteins
    Limitations of Synthetic Nanodiscs:
    • Intolerant to acids and high concentrations of divalent metal ions

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    别名
    CD37 (TSPAN26 产品)
    别名
    Tspan26 Protein, GP52-40 Protein, TSPAN26 Protein, CD37 antigen Protein, CD37 molecule Protein, Cd37 Protein, CD37 Protein
    背景
    The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
    分子量
    The human full length CD37 protein has a MW of 31.7 kDa
    UniProt
    P11049
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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