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- 抗原 See all Claudin 6 (CLDN6) 蛋白
- Claudin 6 (CLDN6)
- 蛋白类型
- Synthetic Nanodisc
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宿主
- 人
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资源
- HEK-293 Cells
- 原理
- Human CLDN6 full length protein-synthetic nanodisc
- 产品特性
- Unlike other membrane scaffold protein (MSP) Nanodisc on the market, our synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Top Product
- Discover our top product CLDN6 蛋白
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Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP
CLDN6 宿主: Cynomolgus 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLPCLDN6 宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC. Imm, ELISA, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-219) (Active) protein-VLPCLDN6 宿主: 小鼠 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Claudin 6 (CLDN6) proteinCLDN6 宿主: 人 宿主: Mammalian Cells MSP Nanodisc
Claudin 6 (CLDN6) (AA 1-220) (Active) protein-VLP (Biotin)CLDN6 宿主: 人 宿主: HEK-293 Cells VLP > 95 % as determined by HPLC Imm, ELISA, Func, SPR Active
Claudin 6 (CLDN6) (AA 1-220) protein (GST tag)CLDN6 宿主: 人 宿主: 小麦胚 Recombinant ELISA, WB, AP, AA
Claudin 6 (CLDN6) (AA 138-160) protein (Fc Tag)CLDN6 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 6 (CLDN6) (AA 138-160) protein (mFc Tag)CLDN6 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 6 (CLDN6) (AA 1-4) protein (mFc Tag)CLDN6 宿主: 人 宿主: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Claudin 6 (CLDN6) protein-VLPCLDN6 宿主: 人 宿主: HEK-293 Cells VLP
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- 说明
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Advantages of Synthetic Nanodiscs:
- Highly purified membrane proteins
- High solubility in aqueous solutions
- High stability
- Proteins are in a native membrane environment and remain biologically active
- No detergent and can be used for cell-based assays
- No MSP backbone proteins
- Intolerant to acids and high concentrations of divalent metal ions
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- Claudin 6 (CLDN6)
- 别名
- CLDN6 (CLDN6 产品)
- 别名
- cldn4l2 Protein, cldn6 Protein, CLDN6 Protein, AL024037 Protein, claudin 6, gene 1 L homeolog Protein, claudin 6 Protein, cldn6.1.L Protein, CLDN6 Protein, Cldn6 Protein
- 背景
- Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.
- 分子量
- The human full length CLDN6 Protein has a MW of 23 kDa
- UniProt
- P56747
- 途径
- Hepatitis C
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