LDLR Protein (AA 22-788) (His tag)
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- 抗原 See all LDLR 蛋白
- LDLR (Low Density Lipoprotein Receptor (LDLR))
- 蛋白类型
- Recombinant
- 产品特性
- AA 22-788
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This LDLR protein is labelled with His tag.
- 原理
- Recombinant Human LDLR Protein with C-terminal 6xHis tag
- 特异性
- LDLR (Ala22-Arg788) 6xHis tag
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Purified from cell culture supernatant by affinity chromatography
- 纯度
- The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
- Top Product
- Discover our top product LDLR 蛋白
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Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His tag)
LDLR 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His-Avi Tag)LDLR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Low Density Lipoprotein Receptor (LDLR) (AA 105-205) protein (GST tag)LDLR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His-Avi Tag,Biotin)LDLR 宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (His tag)LDLR 宿主: Cynomolgus 宿主: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Low Density Lipoprotein Receptor (LDLR) (AA 22-788) (Active) protein (His tag)LDLR 宿主: 人 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
Low Density Lipoprotein Receptor (LDLR) (AA 455-607) protein (His-IF2DI Tag)LDLR 宿主: 人 宿主: 大肠杆菌（E. Coli） Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Low Density Lipoprotein Receptor (LDLR) (AA 1-860) protein (GST tag)LDLR 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AP, AA
Low Density Lipoprotein Receptor (LDLR) (Active) protein (His tag)LDLR 宿主: 小鼠 宿主: HEK-293 Cells Recombinant > 90 % as determined by SDS-PAGE Active
Low Density Lipoprotein Receptor (LDLR) (AA 9-765) (Active) protein (Fc Tag)LDLR 宿主: 兔 宿主: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- LDLR (Low Density Lipoprotein Receptor (LDLR))
- 别名
- LDLR (LDLR 产品)
- 别名
- FH Protein, FHC Protein, LDLCQ2 Protein, Hlb301 Protein, LDLRA Protein, LDLA Protein, LDL receptor-2 Protein, fhc Protein, ldlcq2 Protein, ldlr Protein, ldlr2-a Protein, LDL receptor 1 Protein, ldlr-a Protein, ldlr-b Protein, low density lipoprotein receptor Protein, low density lipoprotein receptor a Protein, low density lipoprotein receptor S homeolog Protein, low density lipoprotein receptor L homeolog Protein, LDLR Protein, Ldlr Protein, ldlra Protein, ldlr.S Protein, ldlr.L Protein
- 背景
- The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
- 分子量
- predicted molecular mass of 85.6 kDa after removal of the signal peptide. The apparent molecular mass of LDLR-His is 100-130 kDa due to glycosylation.
- UniProt
- P01130
- 途径
- Hepatitis C, Lipid Metabolism
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