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CNTF 蛋白

CNTF 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455693
发货至: 中国
  • 抗原 See all CNTF 蛋白
    CNTF (Ciliary Neurotrophic Factor (CNTF))
    蛋白类型
    Recombinant
    宿主
    • 13
    • 8
    • 3
    • 2
    • 2
    • 2
    资源
    • 21
    • 3
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human Ciliary Neurotrophic Factor is produced by our E.coli expression system and the target gene encoding Ala2-Met200 is expressed.
    产品特性
    Extracellular Domain Protein
    纯化方法
    Affinity purification
    纯度
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CNTF 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris-HCl, 100 mM NaCl, pH 8.0.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    CNTF (Ciliary Neurotrophic Factor (CNTF))
    别名
    CNTF (CNTF 产品)
    背景
    Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83 % homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor complexes. CNTF, like FGF acidic, FGF basic, and PD-ECGF (platelet-derived endothelial cell growth factor), does not possess a signal sequence that would allow secretion of the factor by classical secretion pathways. The mechanism underlying the release of CNTF is unknown.
    分子量
    22.93 KDa
    UniProt
    P26441
    途径
    JAK/STAT Signaling
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