CCL5 蛋白
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- 抗原 See all CCL5 蛋白
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- 大肠杆菌(E. Coli)
- 原理
- Recombinant Human C-C Motif Chemokine 5 is produced by our E.coli expression system and the target gene encoding Ser24-Ser91 is expressed.
- 产品特性
- Extracellular Domain Protein
- 纯化方法
- Affinity purification
- 纯度
- Greater than 95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product CCL5 蛋白
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- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 有效期
- 12 months
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- 抗原
- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
- 别名
- CCL5 (CCL5 产品)
- 背景
- Human Chemokine (C-C Motif) Ligand 5 (CCL5) plays an active role in recruiting leukocytes into inflammatory sites. CCL5 is secreted by many cell types at inflammatory sites and it exerts a wide range of activities through the receptors CCR1, CCR3, CCR4, and CCR5. N-Terminal truncated CCL5/RANTES, Met-RANTES, and amino-oxypentane (AOP)-RANTES exhibit antagonist or partial agonist functions on their receptors. CCL5/RANTES attracts different subtypes of leukocytes into inflamed tissue and intervenes in a wide range of allergic and autoimmune diseases.
- 分子量
- 7.8 KDa
- UniProt
- P13501
- 途径
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
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