ELAPOR1
(Endosome/Lysosome-associated Apoptosis and Autophagy Regulator 1 (ELAPOR1))
蛋白类型
Recombinant
宿主
人
资源
HEK-293 Cells
标记
This ELAPOR1 protein is labelled with His tag.
原理
Recombinant Human Endosome/Lysosome-associated Apoptosis and Autophagy Regulator 1 is produced by our Mammalian expression system and the target gene encoding Thr42-Lys910 is expressed with a 6His tag at the C-terminus.
产品特性
Extracellular Domain Protein
纯化方法
Purified from cell culture supernatant by affinity chromatography
纯度
Greater than 95 % as determined by reducing SDS-PAGE.
ELAPOR1
宿主: 人
宿主: HEK-293 Cells
Recombinant
>95 % as determined by SDS-PAGE.
限制
仅限研究用
状态
Lyophilized
缓冲液
Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
储存条件
-20 °C,-80 °C
储存方法
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
有效期
12 months
抗原
ELAPOR1
(Endosome/Lysosome-associated Apoptosis and Autophagy Regulator 1 (ELAPOR1))
Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated with breast and endometrial cancers, but its mechanism of action remains unknown.May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. That EIG121 is a good endometrial biomarker associated with a hyperestrogenic state and estrogen-related type I endometrial adenocarcinoma.