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IL-2 Protein (His tag)

IL2 宿主: 人 宿主: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455647
发货至: 中国
  • 抗原 See all IL-2 (IL2) 蛋白
    IL-2 (IL2) (Interleukin 2 (IL2))
    蛋白类型
    Recombinant
    宿主
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    资源
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    HEK-293 Cells
    标记
    This IL-2 protein is labelled with His tag.
    原理
    Recombinant Human Interleukin-2 Superkine is produced by our Mammalian expression system and the target gene encoding Ala21-Thr153 (L100F, R101D, L105V, I106V, I112F) is expressed with a 6His tag at the C-terminus.
    产品特性
    Extracellular Domain Protein
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    纯度
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product IL2 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    IL-2 (IL2) (Interleukin 2 (IL2))
    别名
    IL-2 (IL2 产品)
    别名
    IL2 Protein, IL-2 Protein, il2 Protein, TCGF Protein, lymphokine Protein, Il-2 Protein, POIL2 Protein, interleukin 2 Protein, interleukin-15 Protein, IL2 Protein, il2 Protein, LOC100303688 Protein, Il2 Protein
    背景
    Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system, belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. New research has shown that IL-2 mutant reduced toxicity while being more potent at stimulating anti-tumor effector immune cells.
    分子量
    16.5 KDa
    UniProt
    P60568
    途径
    JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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