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MYDGF Protein (His tag)

D17Wsu104e 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455641
发货至: 中国
  • 抗原 See all MYDGF (D17Wsu104e) 蛋白
    MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))
    蛋白类型
    Recombinant
    宿主
    资源
    • 2
    • 1
    大肠杆菌(E. Coli)
    标记
    This MYDGF protein is labelled with His tag.
    原理
    Recombinant Human Myeloid-derived Growth Factor is produced by our E.coli expression system and the target gene encoding Ser33-Leu173 is expressed with a 6His tag at the N-terminus.
    产品特性
    Extracellular Domain Protein
    纯化方法
    Affinity purification
    纯度
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product D17Wsu104e 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 4 mM HCl.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    MYDGF (D17Wsu104e) (DNA segment, Chr 17, Wayne State University 104, expressed (D17Wsu104e))
    别名
    MYDGF (D17Wsu104e 产品)
    别名
    EUROIMAGE1875335 Protein, IL25 Protein, IL27 Protein, IL27w Protein, R33729_1 Protein, SF20 Protein, Il25 Protein, Ly6elg Protein, myeloid derived growth factor Protein, MYDGF Protein, Mydgf Protein
    背景
    Myeloid-derived growth factor (MYDGF) is a secreted protein which belongs to the UPF0556 family. MYDGF was strongly expressed in spleen, prostate and lung, and weakly expressed in the left ventricle and liver. Bone marrow-derived monocyte and paracrine-acting protein promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). MYDGF stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. It inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. MYDGF is involved in endothelial cell proliferation and angiogenesis. It may serve as a prototypical example for the development of protein-based therapies for ischemic tissue repair.
    分子量
    18 KDa
    UniProt
    Q969H8
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