CCL18
(Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
蛋白类型
Recombinant
宿主
人
资源
大肠杆菌(E. Coli)
标记
This CCL18 protein is labelled with His tag.
原理
Recombinant Human C-C Motif Chemokine 18 is produced by our E.coli expression system and the target gene encoding Ala21-Ala89 is expressed with a 6His tag at the N-terminus.
产品特性
Extracellular Domain Protein
纯化方法
Affinity purification
纯度
Greater than 95 % as determined by reducing SDS-PAGE.
Lyophilized from a 0.2 μm filtered solution of PBS, 5 % Trehalose, pH 7.4.
储存条件
-20 °C,-80 °C
储存方法
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
有效期
12 months
抗原
CCL18
(Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
C-C Motif Chemokine 18 (CCL18) is secreted protein that belongs to the intercrine beta (chemokine CC) family. CCL18 is expressed at high levels in the lung, lymph nodes, placenta, bone marrow, and dendritic cells. CCL18 is a chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. CCL18 may be involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It has chemotactic activity for naive T-cells, CD4 and CD8 T-cells and thus may play a role in both humoral and cell-mediated immunity responses.