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PDGF-BB Homodimer 蛋白

宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 98 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455626
发货至: 中国
  • 抗原
    PDGF-BB Homodimer
    蛋白类型
    Recombinant
    宿主
    • 8
    • 4
    • 3
    资源
    • 10
    • 2
    • 1
    • 1
    大肠杆菌(E. Coli)
    原理
    Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli expression system and the target gene encoding Ser82-Thr190 is expressed.
    产品特性
    Extracellular Domain Protein
    纯化方法
    Affinity purification
    纯度
    Greater than 98 % as determined by reducing SDS-PAGE.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM NaAc-HAc, pH 4.5.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    PDGF-BB Homodimer
    别名
    PDGF-BB
    别名
    PDGF-2 Protein, PDGF2 Protein, SIS Protein, SSV Protein, c-sis Protein, PDGF-B Protein, Sis Protein, platelet derived growth factor subunit B Protein, platelet derived growth factor, B polypeptide Protein, PDGFB Protein, Pdgfb Protein
    背景
    Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
    分子量
    12.42 KDa
    UniProt
    P01127
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