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Oncostatin M Protein (OSM) (His tag)

OSM 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455625
发货至: 中国
  • 抗原 See all Oncostatin M (OSM) 蛋白
    Oncostatin M (OSM)
    蛋白类型
    Recombinant
    宿主
    • 23
    • 5
    • 4
    • 3
    • 1
    • 1
    资源
    • 19
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    大肠杆菌(E. Coli)
    标记
    This Oncostatin M protein is labelled with His tag.
    原理
    Recombinant Human Oncostatin M is produced by our E.coli expression system and the target gene encoding Ala26-Arg221 is expressed with a 6His tag at the N-terminus.
    产品特性
    Extracellular Domain Protein
    纯化方法
    Affinity purification
    纯度
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product OSM 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mMTris-HCl, 1 mM EDTA, 200 mM NaCl, pH 7.5.
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    Oncostatin M (OSM)
    别名
    OSM (OSM 产品)
    别名
    OSM Protein, OncoM Protein, oncostatin M Protein, OSM Protein, Osm Protein
    背景
    Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological activities through specific cell surface receptors. The low affinity LIF receptor that shares the similarity of containing protein gp130 has now been identified to be a component of a high- affinity OSM receptor that will transduce OSM signals. OSM has also been shown to play a role in both pro and anti-inflammatory actions. OSM may also be involved in many biometabolism processes including liver development, haematopoeisis, inflammation, bone formation and destruction and possibly CNS development.
    分子量
    24.44 KDa
    UniProt
    P13725
    途径
    JAK/STAT Signaling, Negative Regulation of Hormone Secretion
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