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CCL26 蛋白

CCL26 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
产品编号 ABIN7455613
发货至: 中国
  • 抗原 See all CCL26 蛋白
    CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))
    蛋白类型
    Recombinant
    宿主
    资源
    • 4
    • 2
    大肠杆菌(E. Coli)
    原理
    Recombinant Human C-C Motif Chemokine 26 is produced by our E.coli expression system and the target gene encoding Ser27-Leu94 is expressed.
    产品特性
    Extracellular Domain Protein
    纯化方法
    Affinity purification
    纯度
    Greater than 95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product CCL26 蛋白
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
    储存条件
    4 °C,-20 °C
    储存方法
    Lyophilized protein should be stored at -20°C or lower, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at -20°C or lower for 3 months. The product is shipped at ambient temperature. Upon receipt, store it immediately at the proper temperature.
    有效期
    12 months
  • 抗原
    CCL26 (Chemokine (C-C Motif) Ligand 26 (CCL26))
    别名
    CCL26 (CCL26 产品)
    别名
    CCL26 Protein, IMAC Protein, MIP-4a Protein, MIP-4alpha Protein, SCYA26 Protein, TSC-1 Protein, Ccl26l Protein, C-C motif chemokine ligand 26 Protein, chemokine (C-C motif) ligand 26 Protein, CCL26 Protein, Ccl26 Protein
    背景
    Chemokine (C C Motif) Ligand 26 (CCL26) is a novel small cytokine belonging to the CC chemokine family, which involved in immunoregulatory and inflammatory processes. CCL26 is expressed constitutively in thymus, but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells. It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4. Eotaxin-3/CCL26, along with Eotaxin-1 and Eotaxin-2, selectively activates the CC chemokine receptor 3 (CCR3). The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma. The full-length cDNA for Eotaxin-3 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues. Both the 71 and 68 amino acid residue variants of recombinant Eotaxin-3 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line. Unlike most other CC chemokines, Eotaxin-3 maps to human chromosome 7q11.2, within 40 kilobases of the Eotaxin-2 loci. Eotaxin-3 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.
    分子量
    Predicted MW is 8.21 Kda. Protein runs at 13KDa under reducing conditions.
    UniProt
    Q9Y258
    途径
    Regulation of Actin Filament Polymerization
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