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HLA-A*01:01 (Tetramer) protein (MAGE-A3)

宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7454317
发货至: 中国
  • 抗原
    HLA-A*01:01
    蛋白类型
    Recombinant
    产品特性
    Tetramer
    宿主
    资源
    • 4
    • 1
    HEK-293 Cells
    标记
    MAGE-A3
    原理
    Human HLA-A*01:01 & B2M & MAGE-A3 (EVDPIGHLY) Tetramer Protein
    序列
    Gly25-Thr305 (HLA-A*01:01), Ile21-Met119 (B2M) and EVDPIGHLY peptide
    特异性
    Uni-Prot: Q5SUL5 (HLA-A*01:01), P61769 (B2M), EVDPIGHLY
    产品特性
    Recombinant Human MAGE-A3(HLA-A*01:01) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*01:01),Ile21-Met119(B2M) and EVDPIGHLY peptide.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HLA-A*01:01
    背景
    Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine immunotherapy in patients with PCa.
    分子量
    258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
    UniProt
    Q5SUL5
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