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HLA-A*11:01 (Monomer) protein (Biotin,KRAS)

宿主: 人 宿主: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
产品编号 ABIN7454303
发货至: 中国
  • 抗原
    HLA-A*11:01
    蛋白类型
    Recombinant
    产品特性
    Monomer
    宿主
    资源
    • 31
    • 6
    • 1
    HEK-293 Cells
    标记
    Biotin,KRAS
    原理
    Biotinylated Human HLA-A*11:01 & B2M & KRAS WT (VVVGAGGVGK) Monomer Protein
    序列
    Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and VVVGAGGVGK peptide
    特异性
    Uni-Prot: AAV53343.1 (HLA-A*11:01), P61769 (B2M), VVVGAGGVGK
    产品特性
    Recombinant Biotinylated Human HLA-A*11:01 & B2M & KRAS WT (VVVGAGGVGK) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*11:01),Ile21-Met119(B2M) and VVVGAGGVGK peptide.
    纯度
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    过滤
    0.22 μm filtered
    内毒素水平
    Less than 1EU per μg by the LAL method.
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    缓冲液
    Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    储存条件
    -20 °C,-80 °C
    储存方法
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    HLA-A*11:01
    背景
    Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target.
    分子量
    50.30 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.
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