MADCAM1 Protein (Biotin,Fc-Avi Tag)
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- 抗原 See all MADCAM1 蛋白
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- 蛋白类型
- Recombinant
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宿主
- 人
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资源
- HEK-293 Cells
- 标记
- This MADCAM1 protein is labelled with Biotin,Fc-Avi Tag.
- 原理
- Biotinylated Human MAdCAM-1 Protein, Fc,Avitag™ (MALS verified)
- 序列
- Gln 19- Gln 333
- 产品特性
- Biotinylated Human MAdCAM-1, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Gln 19- Gln 333 (Accession # Q4PKD0-1).
- 纯度
- 95,00 %
- 内毒素水平
- 1.0 EU per μg
- 质量等级
- MALS verified
- Top Product
- Discover our top product MADCAM1 蛋白
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- 说明
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This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 63 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- PBS, pH 7.4
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- MADCAM1 (Mucosal Vascular Addressin Cell Adhesion Molecule 1 (MADCAM1))
- 别名
- MAdCAM-1 (MADCAM1 产品)
- 别名
- MACAM1 Protein, AV211525 Protein, mucosal vascular addressin cell adhesion molecule 1 Protein, MADCAM1 Protein, Madcam1 Protein
- 背景
- Synonyms:MAdCAM-1,Mucosal vascular addressin cell adhesion molecule 1 transcript variant 1,Description:The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the α4β7 integrin expressed on lymphocytes.
- 分子量
- 63 kDa
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