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C5 Protein (Biotin,His-Avi Tag)

C5 宿主: 人 宿主: HEK-293 Cells Recombinant 95,00 %
产品编号 ABIN7316821
发货至: 中国
  • 抗原 See all C5 蛋白
    C5 (Complement Component 5 (C5))
    蛋白类型
    Recombinant
    宿主
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    资源
    • 6
    • 5
    • 3
    • 1
    HEK-293 Cells
    标记
    This C5 protein is labelled with Biotin,His-Avi Tag.
    原理
    Biotinylated Human Complement C5 Protein, His,Avitag™
    序列
    Gln 19 - Cys 1676
    产品特性
    Biotinylated Human Complement C5, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Cys 1676 (Accession # P01031-1).
    纯度
    95,00 %
    内毒素水平
    1.0 EU per μg
    Top Product
    Discover our top product C5 蛋白
  • 说明

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 189.9 kDa. As a result of glycosylation, the protein migrates as 75 kDa, 120 kDa and 200 kDa under reducing (R) condition, and 200 kDa under non-reducing (NR) condition (SDS-PAGE).

    限制
    仅限研究用
  • 状态
    Lyophilized
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C
    储存方法
    -20°C
  • 抗原
    C5 (Complement Component 5 (C5))
    别名
    Complement C5 (C5 产品)
    别名
    C5 Protein, LOC565774 Protein, C5a Protein, C5b Protein, CPAMD4 Protein, Hc Protein, RGD1561905 Protein, He Protein, complement C5 Protein, complement component 5 Protein, hemolytic complement Protein, C5 Protein, c5 Protein, Hc Protein
    背景
    Synonyms:Complement C5,C5,CPAMD4,Description:Derived from proteolytic degradation of complement C5, C5 anaphylatoxin is a mediator of local inflammatory process. C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain). Activation of C5 by a C5 convertase initiates the spontaneous assembly of the late complement components, C5-C9, into the membrane attack complex. C5b has a transient binding site for C6. The C5b-C6 complex is the foundation upon which the lytic complex is assembled. The C5a anaphylatoxin interacts with C5AR1 and tick complement inhibitor. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.
    分子量
    189.9 kDa
    NCBI登录号
    NP_001726
    途径
    Complement System, Carbohydrate Homeostasis
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