Complement C2 Protein (His tag)
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- 抗原 See all Complement C2 蛋白
- Complement C2
- 蛋白类型
- Recombinant
- 生物活性
- Active
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宿主
- Cynomolgus
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资源
- HEK-293 Cells
- 标记
- This Complement C2 protein is labelled with His tag.
- 原理
- Cynomolgus Complement C2 Protein, His Tag (active enzyme)
- 序列
- Ala 21 - Leu 752
- 产品特性
- Cynomolgus Complement C2, His Tag is expressed from human 293 cells (HEK293). It contains AA Ala 21 - Leu 752 (Accession # G8F3W0-1).
- 纯度
- 95,00 %
- 内毒素水平
- 1.0 EU per μg
- Biological Activity Comment
- Measured by its ability to cleave a colorimetric peptide substrate, N-carbobenzyloxy-Gly-Arg-ThioBenzyl ester (Z-GR-SBzl), in the presence of 5,5’Dithio-bis (2-nitrobenzoic acid) (DTNB).The specific activity is >100 pmol/min/µg (QC tested).
- Top Product
- Discover our top product Complement C2 蛋白
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- 说明
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This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 83.0 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 缓冲液
- 20 mM Tris,150 mM NaCl,Ph 7.5
- 储存条件
- -20 °C
- 储存方法
- -20°C
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- 抗原
- Complement C2
- Abstract
- Complement C2 产品
- 别名
- CO2 Protein, complement C2 Protein, complement component 2 (within H-2S) Protein, C2 Protein
- 背景
- Synonyms:C2,Complement C2,Complement Component C2,Description:C2 is a major histocompatibility complex class-III protein. Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase. The lectin (LP) and classical (CP) pathways are two of the three main activation cascades of the complement system. These pathways start with recognition of different pathogen- or danger-associated molecular patterns and include identical steps of proteolytic activation of complement component C4, formation of the C3 proconvertase C4b2, followed by cleavage of complement component C2 within C4b2 resulting in the C3 convertase C4b2a.
- 分子量
- 83.0 kDa
- NCBI登录号
- XP_005553508
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