SEZ6 Protein (AA 20-927) (His tag)
-
- 抗原 See all SEZ6 蛋白
- SEZ6 (Seizure Related 6 Homolog (SEZ6))
- 蛋白类型
- Recombinant
- 产品特性
- AA 20-927
-
宿主
- Cynomolgus
-
资源
- HEK-293 Cells
- 标记
- This SEZ6 protein is labelled with His tag.
- 原理
- Cynomolgus SEZ6 Protein
- 序列
- Leu20-His927
- 产品特性
- Recombinant Cynomolgus SEZ6 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu20-His927.
- 纯度
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- 过滤
- 0.22 μm filtered
- 内毒素水平
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Cynomolgus SEZ6, His Tag at 5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-SEZ6 Antibody, hFc Tag with the EC50 of 22.7ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product SEZ6 蛋白
-
-
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 溶解方式
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- 缓冲液
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- SEZ6 (Seizure Related 6 Homolog (SEZ6))
- 别名
- SEZ6 (SEZ6 产品)
- 别名
- BSRP-C Protein, D11Bhm177e Protein, mKIAA4158 Protein, sez-6 Protein, seizure related gene 6 Protein, seizure related 6 homolog Protein, Sez6 Protein, SEZ6 Protein
- 背景
- Seizure-related protein 6 (Sez6) contributes to chronic pain development as sez6 knockout mice show attenuated pain behaviours after peripheral nerve injury, compared with control mice. The type I transmembrane isoform of Sez6 is cleaved by the β-amyloid precursor protein cleavage enzyme 1 (BACE1), resulting in Sez6 extracellular domain shedding from the neuron surface.
- 分子量
- 99.11 kDa. Due to glycosylation, the protein migrates to 150-180 kDa based on Tris-Bis PAGE result.
- UniProt
- A0A2K5WPJ4
- 途径
- Synaptic Membrane
-